SCHEMBL29913293

SCHEMBL29913293

Nc1nccn2c(C3CCC(CO)OC3)nc(-c3ccc(Oc4ccccc4)c(F)c3F)c12

nearest known ligand 0.73

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TNK2 Q07912 18/20 0.73
IGF1R P08069 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29913314 1.00 TNK2 (0.73) TNK2IGF1R
SCHEMBL29913289 1.00 TNK2 (0.73) TNK2IGF1R
SCHEMBL29913329 1.00 TNK2 (0.73) TNK2IGF1R
SCHEMBL29913353 1.00 TNK2 (0.73) TNK2IGF1R
SCHEMBL23625327 0.88 TNK2 (0.72) TNK2
SCHEMBL29913310 0.88 TNK2 (0.72) TNK2
SCHEMBL29913383 0.88 TNK2 (0.72) TNK2
SCHEMBL29913451 0.88 TNK2 (0.72) TNK2
SCHEMBL29913460 0.88 TNK2 (0.72) TNK2
SCHEMBL29913577 0.86 TNK2 (0.55) TNK2IGF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120118089-A BTK inhibitors 迪哲(江苏)医药股份有限公司 2025-06-10 CN claimed
CN-115989231-B Compound serving as BTK inhibitor and preparation method and application thereof 成都海博为药业有限公司 2025-04-01 CN claimed
CN-114945574-B BTK inhibitors 迪哲(江苏)医药股份有限公司 2025-02-07 CN claimed
EP-4087845-A1 BTK INHIBITORS DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) 2022-11-16 EP claimed
CN-114945574-A BTK inhibitors 迪哲(江苏)医药股份有限公司 2022-08-26 CN claimed
CN-120118089-A BTK inhibitors 迪哲(江苏)医药股份有限公司 2025-06-10 CN disclosed
CN-114945574-B BTK inhibitors 迪哲(江苏)医药股份有限公司 2025-02-07 CN disclosed
EP-4087845-A1 BTK INHIBITORS DIZAL (JIANGSU) PHARMACEUTICAL CO., LTD. (CN) 2022-11-16 EP disclosed
CN-114945574-A BTK inhibitors 迪哲(江苏)医药股份有限公司 2022-08-26 CN disclosed