Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 11/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | TNKS | O95271 | 2/20 | 0.70 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 2/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | PBRM1 | Q86U86 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5248973 | 1.00 | TNKS2 (1.00) | TNKS2ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL6124101 | 0.89 | TNKS2 (0.80) | TNKS2ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL6124107 | 0.89 | TNKS2 (0.80) | TNKS2ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL6124214 | 0.89 | TNKS2 (0.80) | TNKS2ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL30996133 | 0.85 | TNKS2 (0.74) | TNKS2ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL30996130 | 0.85 | TNKS2 (0.74) | TNKS2ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL28838022 | 0.85 | KMT2A (1.00) | TNKS2ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL257093 | 0.85 | TNKS2 (1.00) | TNKS2ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL29913643 | 0.85 | TNKS2 (1.00) | TNKS2ALDH1A1KDM4EHSD17B10KMT2A | |
| SCHEMBL6124104 | 0.85 | TNKS2 (0.73) | TNKS2ALDH1A1KDM4EHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354556-B | C (C)3Chiral ligand H containing symmetrical amide bond3L, preparation method and application | 合肥工业大学 | 2024-07-09 | — | — | CN | claimed |
| CN-116178283-B | 2-Phenyl-2, 3-dihydro-quinazolin-4 (1H) -one derivative, preparation and application thereof | 武汉科技大学 | 2024-07-02 | — | — | CN | claimed |
| CN-116178283-A | 2-phenyl-2, 3-dihydro-quinazolin-4 (1H) -one derivative, preparation and application thereof | 武汉科技大学 | 2023-05-30 | — | — | CN | claimed |
| CN-113354556-B | C (C)3Chiral ligand H containing symmetrical amide bond3L, preparation method and application | 合肥工业大学 | 2024-07-09 | — | — | CN | disclosed |
| CN-116178283-B | 2-Phenyl-2, 3-dihydro-quinazolin-4 (1H) -one derivative, preparation and application thereof | 武汉科技大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-116178283-B | 2-Phenyl-2, 3-dihydro-quinazolin-4 (1H) -one derivative, preparation and application thereof | 武汉科技大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-116178283-B | 2-Phenyl-2, 3-dihydro-quinazolin-4 (1H) -one derivative, preparation and application thereof | 武汉科技大学 | 2024-07-02 | — | — | CN | disclosed |
| CN-115433134-B | Catalytic enantioselective synthesis method of dihydroquinazolinone | 哈尔滨工业大学（深圳） | 2024-05-28 | — | — | CN | disclosed |
| CN-115160235-B | 2, 3-dihydro-quinazoline-4 (1H) -ketone compound and ultrasonic synthesis method thereof | 宜宾学院 | 2023-12-15 | — | — | CN | disclosed |
| CN-116178283-A | 2-phenyl-2, 3-dihydro-quinazolin-4 (1H) -one derivative, preparation and application thereof | 武汉科技大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-116178283-A | 2-phenyl-2, 3-dihydro-quinazolin-4 (1H) -one derivative, preparation and application thereof | 武汉科技大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-116178283-A | 2-phenyl-2, 3-dihydro-quinazolin-4 (1H) -one derivative, preparation and application thereof | 武汉科技大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-114874448-B | Preparation method and application of metal organic framework material with grading holes | 中国科学技术大学 | 2023-04-21 | — | — | CN | disclosed |
| CN-115433134-A | Catalytic enantioselective synthesis method of dihydro quinazolinone | 哈尔滨工业大学（深圳） | 2022-12-06 | — | — | CN | disclosed |
| CN-115160235-A | 2, 3-dihydroquinazoline-4 (1H) -ketone compound and ultrasonic synthesis method thereof | 宜宾学院 | 2022-10-11 | — | — | CN | disclosed |