Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 9/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | EGFR | P00533 | 1/20 | 0.71 |
| ▸ | TNKS | O95271 | 2/20 | 0.69 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.69 |
| ▸ | MAPT | P10636 | 2/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29265402 | 0.95 | TNKS2 (0.91) | TNKS2ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL29913499 | 0.85 | TNKS2 (1.00) | TNKS2ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL5248973 | 0.85 | TNKS2 (1.00) | TNKS2ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL29010904 | 0.84 | EGFR (1.00) | TNKS2ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL29913643 | 0.83 | TNKS2 (1.00) | TNKS2ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL30996130 | 0.83 | TNKS2 (0.74) | TNKS2ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL30996133 | 0.83 | TNKS2 (0.74) | TNKS2ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL6124214 | 0.83 | TNKS2 (0.80) | TNKS2ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL28838022 | 0.83 | KMT2A (1.00) | TNKS2ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL6124107 | 0.83 | TNKS2 (0.80) | TNKS2ALDH1A1KMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354556-B | C (C)3Chiral ligand H containing symmetrical amide bond3L, preparation method and application | 合肥工业大学 | 2024-07-09 | — | — | CN | claimed |
| CN-113354556-B | C (C)3Chiral ligand H containing symmetrical amide bond3L, preparation method and application | 合肥工业大学 | 2024-07-09 | — | — | CN | disclosed |
| CN-115160235-B | 2, 3-dihydro-quinazoline-4 (1H) -ketone compound and ultrasonic synthesis method thereof | 宜宾学院 | 2023-12-15 | — | — | CN | disclosed |
| CN-115160235-A | 2, 3-dihydroquinazoline-4 (1H) -ketone compound and ultrasonic synthesis method thereof | 宜宾学院 | 2022-10-11 | — | — | CN | disclosed |
| CN-103228141-B | Substituted fused pyrimidinones and dihydropyrimidinones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-20 | — | — | CN | disclosed |
| US-20150173359-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER IP GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| US-20150173359-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER IP GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| US-20150173359-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER IP GMBH (DE) | 2015-06-25 | — | — | US | disclosed |
| US-9006265-B2 | Substituted fused pyrimidinones and dihydropyrimidinones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-14 | — | — | US | disclosed |
| US-9006265-B2 | Substituted fused pyrimidinones and dihydropyrimidinones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-14 | — | — | US | disclosed |
| US-9006265-B2 | Substituted fused pyrimidinones and dihydropyrimidinones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-04-14 | — | — | US | disclosed |
| US-20120157306-A1 | Substituted Fused Pyrimidinones and Dihydropyrimidinones | BAYER CROPSCIENCE AG (DE) | 2012-06-21 | — | — | US | disclosed |
| US-20120157306-A1 | Substituted Fused Pyrimidinones and Dihydropyrimidinones | BAYER CROPSCIENCE AG (DE) | 2012-06-21 | — | — | US | disclosed |
| US-20120157306-A1 | Substituted Fused Pyrimidinones and Dihydropyrimidinones | BAYER CROPSCIENCE AG (DE) | 2012-06-21 | — | — | US | disclosed |
| WO-2012028578-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | BAYER CROPSCIENCE AG (DE) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150173359-A1 | SUBSTITUTED FUSED PYRIMIDINONES AND DIHYDROPYRIMIDINONES | DHPS, FDPS, DPYD | TNKS2 3993/4885ALDH1A1 333/4885KMT2A 3719/4885 |
| US-20120157306-A1 | Substituted Fused Pyrimidinones and Dihydropyrimidinones | DHPS, FDPS, DPYD | TNKS2 3993/4885ALDH1A1 333/4885KMT2A 3719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.