Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | CES1 | P23141 | 1/20 | 0.49 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31592687 | 1.00 | L3MBTL1 (0.56) | L3MBTL1MTNR1AMTNR1BAOC3PARP1 | |
| SCHEMBL8752178 | 1.00 | L3MBTL1 (0.56) | L3MBTL1MTNR1AMTNR1BAOC3PARP1 | |
| SCHEMBL6121064 | 1.00 | L3MBTL1 (0.56) | L3MBTL1MTNR1AMTNR1BAOC3PARP1 | |
| SCHEMBL31505889 | 1.00 | L3MBTL1 (0.56) | L3MBTL1MTNR1AMTNR1BAOC3PARP1 | |
| SCHEMBL9457197 | 1.00 | L3MBTL1 (0.56) | L3MBTL1MTNR1AMTNR1BAOC3PARP1 | |
| Hydrochloric Acid SCHEMBL28851336 | 0.98 | L3MBTL1 (0.55) | L3MBTL1MTNR1AMTNR1BAOC3PARP1 | |
| SCHEMBL21194008 | 0.91 | L3MBTL1 (0.49) | L3MBTL1MTNR1AMTNR1BAOC3PARP1 | |
| SCHEMBL6120583 | 0.86 | ATM (0.48) | L3MBTL1MTNR1AMTNR1BAOC3TDP1 | |
| SCHEMBL6390839 | 0.86 | L3MBTL1 (0.60) | L3MBTL1MTNR1AMTNR1BAOC3PARP1 | |
| SCHEMBL14032279 | 0.85 | L3MBTL1 (0.55) | L3MBTL1MTNR1AMTNR1BAOC3PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109790114-B | Novel chiral ligand, metal chelate, various unnatural amino acids and synthesis method of maraviroc and key intermediate thereof | 中国科学院上海药物研究所 | 2025-03-07 | — | — | CN | disclosed |
| CN-117480161-A | Novel 2, 3-dihydro-1H-pyrrolo [3,2-b ] pyridine derivatives as sigma ligands | 塔拉森调理公司 | 2024-01-30 | — | — | CN | disclosed |
| EP-4305029-A1 | NEW 2,3-DIHYDRO-1H-PYRROLO[3,2-B]PYRIDINE DERIVATIVES AS SIGMA LIGANDS | Acondicionamiento Tarrasense (ES) | 2024-01-17 | — | — | EP | disclosed |
| WO-2022189392-A1 | NEW 2,3-DIHYDRO-1H-PYRROLO[3,2-b]PYRIDINE DERIVATIVES AS SIGMA LIGANDS | ACONDICIONAMIENTO TARRASENSE (ES) | 2022-09-15 | — | — | WO | disclosed |