Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19962252 | 0.74 | PKM (0.44) | PKMKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL16889896 | 0.66 | HSD17B10 (0.54) | PKMKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL13973078 | 0.64 | HPGD (0.61) | PKMKDM4EALDH1A1TSHRPOLB | |
| SCHEMBL18659826 | 0.64 | PKM (0.36) | PKMKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL13652681 | 0.62 | POLB (0.52) | PKMKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL15199108 | 0.61 | HSD17B10 (0.49) | PKMKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL24418009 | 0.60 | PKM (0.41) | PKMKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL14315407 | 0.60 | HSD17B10 (0.48) | PKMKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL2820709 | 0.60 | EPHX1 (0.57) | PKMKDM4EALDH1A1POLBHPGD | |
| SCHEMBL11128751 | 0.60 | EPHX1 (0.47) | PKMKDM4EALDH1A1TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160305-A | Amide compound containing 4, 5-dihydroisoxazole, salt thereof, preparation method and application | 华东理工大学 | 2022-10-11 | — | — | CN | disclosed |