SCHEMBL29913745

SCHEMBL29913745

Cc1c(C#N)cc(C#N)c(C)c1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
AR P10275 6/20 0.36
GRIN2D O15399 1/20 0.34
GRIN3B O60391 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2A Q12879 1/20 0.34
GRIN2B Q13224 1/20 0.34
GRIN2C Q14957 1/20 0.34
GRIN3A Q8TCU5 1/20 0.34
ALDH1A1 P00352 3/20 0.33
KDM4E B2RXH2 3/20 0.33
CYP2A6 P11509 1/20 0.33
MEN1 O00255 1/20 0.33
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14349076 0.86 TSHR (0.42) TSHRARGRIN2DGRIN3BGRIN1
SCHEMBL22579171 0.82 TSHR (0.39) TSHRGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL16122316 0.82 TRPV4 (0.35) TSHRARTRPV4
SCHEMBL19009014 0.82 TRPV4 (0.45) TSHRARALDH1A1TRPV4
SCHEMBL21425352 0.82 ESR1 (0.44) TSHRARIMPDH2
SCHEMBL11948728 0.79 TSHR (0.40) TSHRARGRIN2DGRIN3BGRIN1
SCHEMBL17570556 0.78 TSHR (0.36) TSHRGRIN2DGRIN3BGRIN1GRIN2A
SCHEMBL1585098 0.78 AR (0.52) TSHRARALDH1A1KDM4ECYP2A6
SCHEMBL3955231 0.77 TTR (0.42) TSHRARGRIN2DGRIN3BGRIN1
SCHEMBL16127307 0.77 TSHR (0.39) TSHRALDH1A1KDM4EMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115175951-A Resin composition, cured product, prepreg, metal foil-clad laminate, resin sheet, and printed wiring board 三菱瓦斯化学株式会社 2022-10-11 CN disclosed