Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.49 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 7/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | LAP3 | P28838 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.36 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30718534 | 0.94 | F2 (0.49) | F2SPPL2AFEN1ALOX5APCSNK1E | |
| SCHEMBL8178414 | 0.89 | F2 (0.54) | F2SPPL2ACSNK1ELAP3ANPEP | |
| SCHEMBL29913704 | 0.87 | F2 (0.52) | F2 | |
| SCHEMBL30718537 | 0.87 | F2 (0.52) | F2 | |
| SCHEMBL30718508 | 0.82 | F2 (0.48) | F2SPPL2ACSNK1ELAP3ANPEP | |
| SCHEMBL30718544 | 0.81 | F2 (0.47) | F2SPPL2AFEN1ALOX5APCSNK1E | |
| SCHEMBL6066041 | 0.81 | F2 (0.51) | F2SPPL2AFEN1ALOX5APCSNK1E | |
| SCHEMBL4373557 | 0.81 | F2 (0.51) | F2SPPL2AFEN1ALOX5APCSNK1E | |
| SCHEMBL29913751 | 0.81 | F2 (0.52) | F2SPPL2A | |
| SCHEMBL29913816 | 0.80 | F2 (0.46) | F2SPPL2ALAP3ANPEPRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113277991-B | Nitrogen heterocyclic ring amino derivative, preparation method thereof and anti-HIV-1 drug | 中国医学科学院医药生物技术研究所 | 2022-07-12 | — | — | CN | disclosed |