Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.54 |
| ▸ | SPPL2A | Q8TCT8 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 4/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.38 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.38 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30718534 | 0.92 | F2 (0.49) | F2SPPL2ALAP3ANPEPRNPEP | |
| SCHEMBL29913880 | 0.89 | F2 (0.49) | F2SPPL2ALAP3ANPEPRNPEP | |
| SCHEMBL5074473 | 0.86 | F2 (0.53) | F2SPPL2AALDH1A1CA2 | |
| Hydrochloric Acid SCHEMBL1548337 | 0.85 | F2 (0.53) | F2SPPL2AALDH1A1CA2 | |
| SCHEMBL2578881 | 0.81 | ADRB3 (0.39) | ANPEPMCL1ADRB2 | |
| SCHEMBL30718508 | 0.80 | F2 (0.48) | F2SPPL2ALAP3ANPEPRNPEP | |
| SCHEMBL30718544 | 0.79 | F2 (0.47) | F2SPPL2ALAP3ANPEPRNPEP | |
| SCHEMBL4373557 | 0.79 | F2 (0.51) | F2SPPL2ALAP3ANPEPRNPEP | |
| SCHEMBL6066041 | 0.79 | F2 (0.51) | F2SPPL2ALAP3ANPEPRNPEP | |
| SCHEMBL29913751 | 0.78 | F2 (0.52) | F2SPPL2AALDH1A1CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE43596-E1 | α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | G.D. SEARLE LLC (US) | 2012-08-21 | — | — | US | disclosed |
| US-6060476-A | α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 2000-05-09 | — | — | US | disclosed |