SCHEMBL29914248

SCHEMBL29914248

CCO[C@@]1(n2ccc(=S)[nH]c2=O)O[C@H](CO)[C@@H](O)[C@H]1O

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
P2RY14 Q15391 2/20 0.35
P2RY6 Q15077 4/20 0.35
P2RY2 P41231 4/20 0.35
P2RY4 P51582 3/20 0.35
SLC28A1 O00337 1/20 0.33
SLC28A2 O43868 1/20 0.33
SLC29A1 Q99808 1/20 0.33
SLC28A3 Q9HAS3 1/20 0.33
PYGB P11216 3/20 0.33
PYGL P06737 2/20 0.33
PYGM P11217 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17745010 0.89 SLC28A1 (0.44) P2RY14P2RY6P2RY2P2RY4SLC28A1
SCHEMBL31439434 0.89 P2RY6 (0.39) P2RY14P2RY6P2RY2P2RY4SLC28A1
SCHEMBL28996776 0.82 SLC28A1 (0.39) P2RY14P2RY6P2RY2P2RY4SLC28A1
SCHEMBL18954926 0.81 P2RY14 (0.35) P2RY14P2RY6P2RY2P2RY4SLC28A1
SCHEMBL23673342 0.80 SLC28A1 (0.43) P2RY14P2RY6P2RY2P2RY4SLC28A1
SCHEMBL29140448 0.77 SLC28A1 (0.42) P2RY14P2RY6P2RY2P2RY4SLC28A1
SCHEMBL2635503 0.77 SLC28A1 (0.46) P2RY14P2RY6P2RY2P2RY4SLC28A1
SCHEMBL3868098 0.77 SLC28A1 (0.40) P2RY14P2RY6P2RY2SLC28A1SLC28A2
SCHEMBL32670136 0.76 SLC28A1 (0.48) P2RY14P2RY6P2RY2P2RY4SLC28A1
SCHEMBL31268771 0.76 SLC28A1 (0.43) P2RY14P2RY6P2RY2P2RY4SLC28A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4305051-A1 CHIMERIC PROTEINS IN AUTOIMMUNITY Shattuck Labs, Inc. (US) 2024-01-17 EP disclosed
WO-2022192236-A1 CHIMERIC PROTEINS IN AUTOIMMUNITY SHATTUCK LABS, INC. (US) 2022-09-15 WO disclosed