Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC28A1 | O00337 | 1/20 | 0.40 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.40 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.40 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732699 | 0.95 | SLC28A1 (0.37) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL861369 | 0.92 | SLC28A1 (0.36) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL18171337 | 0.92 | SLC28A1 (0.36) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL9748569 | 0.92 | SLC28A1 (0.36) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL23673342 | 0.92 | SLC28A1 (0.43) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL6919227 | 0.90 | SLC28A1 (0.40) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL3885391 | 0.90 | SLC28A1 (0.40) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL4326832 | 0.90 | SLC28A1 (0.40) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL1079788 | 0.90 | SLC28A1 (0.40) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 | |
| SCHEMBL17745010 | 0.87 | SLC28A1 (0.44) | SLC28A1SLC28A2SLC29A1SLC28A3P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1450820-A4 | METHOD FOR TREATING OR PREVENTING INFLAMMATORY DISEASES | INSPIRE PHARMACEUTICALS INC (US) | 2009-02-18 | — | — | EP | disclosed |
| EP-1450820-A2 | METHOD FOR TREATING OR PREVENTING INFLAMMATORY DISEASES | Inspire Pharmaceuticals, Inc. (US) | 2004-09-01 | — | — | EP | disclosed |
| WO-2003039473-A2 | METHOD FOR TREATING OR PREVENTING INFLAMMATORY DISEASES | INSPIRE PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | WO | disclosed |