Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1920854 | 0.88 | SETD7 (0.42) | SETD7GPR119MAP4K4NR1H2DRD2 | |
| SCHEMBL15312664 | 0.88 | SETD7 (0.42) | SETD7GPR119MAP4K4NR1H2DRD2 | |
| SCHEMBL19504105 | 0.88 | SETD7 (0.41) | SETD7GPR119MAP4K4NR1H2HDAC1 | |
| SCHEMBL13895338 | 0.88 | SETD7 (0.41) | SETD7GPR119MAP4K4NR1H2HDAC1 | |
| SCHEMBL25873549 | 0.88 | SETD7 (0.41) | SETD7GPR119MAP4K4NR1H2HDAC1 | |
| SCHEMBL28694797 | 0.86 | DRD2 (0.44) | SETD7GPR119MAP4K4NR1H2DRD2 | |
| SCHEMBL3965882 | 0.85 | SETD7 (0.40) | SETD7GPR119MAP4K4NR1H2DRD2 | |
| SCHEMBL3964387 | 0.85 | SETD7 (0.40) | SETD7GPR119MAP4K4NR1H2DRD2 | |
| SCHEMBL21006810 | 0.85 | SETD7 (0.40) | SETD7GPR119MAP4K4NR1H2DRD2 | |
| SCHEMBL17574594 | 0.85 | SETD7 (0.40) | SETD7GPR119MAP4K4NR1H2DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111094300-B | Benzo-heteroaryl derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-09-16 | — | — | CN | disclosed |