Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 3/20 | 0.85 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.82 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.73 |
| ▸ | CXCR4 | P61073 | 6/20 | 0.62 |
| ▸ | MC4R | P32245 | 2/20 | 0.57 |
| ▸ | MC5R | P33032 | 2/20 | 0.57 |
| ▸ | MC3R | P41968 | 2/20 | 0.57 |
| ▸ | MC1R | Q01726 | 2/20 | 0.57 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.57 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.57 |
| ▸ | FCGRT | P55899 | 3/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31088157 | 0.96 | GNRHR (0.83) | GNRHRPTGS1ABCC2CXCR4MC4R | |
| Gonadorelin SCHEMBL29371269 | 0.93 | PTGS1 (0.96) | GNRHRPTGS1ABCC2 | |
| Gonadorelin SCHEMBL29351373 | 0.93 | PTGS1 (0.96) | GNRHRPTGS1ABCC2 | |
| Gonadorelin SCHEMBL22520 | 0.93 | PTGS1 (0.96) | GNRHRPTGS1ABCC2 | |
| Gonadorelin SCHEMBL20856309 | 0.92 | PTGS1 (0.94) | GNRHRPTGS1ABCC2 | |
| Gonadorelin SCHEMBL29359962 | 0.91 | PTGS1 (0.93) | GNRHRPTGS1ABCC2 | |
| Gonadorelin SCHEMBL20856308 | 0.91 | PTGS1 (0.93) | GNRHRPTGS1ABCC2 | |
| Triptorelin SCHEMBL19712233 | 0.90 | PTGS1 (1.00) | GNRHRPTGS1ABCC2 | |
| Triptorelin SCHEMBL30022783 | 0.90 | PTGS1 (1.00) | GNRHRPTGS1ABCC2 | |
| Triptorelin SCHEMBL29903080 | 0.90 | PTGS1 (1.00) | GNRHRPTGS1ABCC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4051309-A1 | LHRH-PACLITAXEL CONJUGATES AND METHODS OF USE | Worcester Polytechnic Institute (US) | 2022-09-07 | — | — | EP | disclosed |
| EP-4051693-A1 | LHRH-PRODIGIOSIN CONJUGATES AND METHODS OF USE | Worcester Polytechnic Institute (US) | 2022-09-07 | — | — | EP | disclosed |