Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MAP2 | P11137 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | DDO | Q99489 | 1/20 | 0.38 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | PRKCI | P41743 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23167061 | 1.00 | RET (0.40) | RETKDRMAP2JAK2CSF1R | |
| SCHEMBL13199581 | 0.85 | PDK2 (0.41) | DAODDOAXLPRKCI | |
| SCHEMBL21417550 | 0.81 | CHEK1 (0.43) | RETKDRJAK2CSF1RMEN1 | |
| SCHEMBL8328040 | 0.79 | MAP2 (0.36) | RETKDRMAP2JAK2CSF1R | |
| SCHEMBL8323760 | 0.76 | CYP3A4 (0.45) | MAP2JAK2CSF1RMEN1KMT2A | |
| SCHEMBL2039383 | 0.74 | NR4A2 (0.50) | MAP2KMT2AHTTLMNA | |
| SCHEMBL8329209 | 0.74 | CHEK1 (0.34) | MAP2JAK2CSF1RMEN1KMT2A | |
| SCHEMBL38663997 | 0.72 | MAP2 (0.48) | MAP2MEN1KMT2AHSD17B10DAO | |
| SCHEMBL15884007 | 0.72 | ACHE (0.50) | MAP2CSF1RMEN1KMT2AHSD17B10 | |
| SCHEMBL4851362 | 0.71 | CSF1R (0.50) | CSF1RMEN1KMT2AHSD17B10DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114746428-B | MCL1 inhibitor and application thereof | 加利福尼亚技术学院 | 2025-05-16 | — | — | CN | disclosed |
| CN-114746428-A | MCL1 inhibitor and application thereof | 加利福尼亚技术学院 | 2022-07-12 | — | — | CN | disclosed |