Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 8/20 | 0.43 |
| ▸ | SLC16A1 | P53985 | 8/20 | 0.43 |
| ▸ | MCTS1 | Q9ULC4 | 5/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29915480 | 0.87 | TP53 (0.44) | SLC16A3SLC16A1MCTS1MAPTMAPK1 | |
| SCHEMBL22613692 | 0.87 | SLC16A3 (0.47) | SLC16A3SLC16A1MCTS1DYRK1ACLK4 | |
| SCHEMBL29915468 | 0.86 | PTGDR (0.42) | DYRK1ACLK4PTGDRALDH1A1KDM4E | |
| SCHEMBL29915420 | 0.85 | SLC16A3 (0.46) | SLC16A3SLC16A1MCTS1MAPT | |
| SCHEMBL29915303 | 0.85 | NPC1 (0.42) | SLC16A3SLC16A1MCTS1MAPTLMNA | |
| SCHEMBL22613701 | 0.81 | SLC16A3 (0.48) | SLC16A3SLC16A1MCTS1DYRK1ACLK4 | |
| SCHEMBL29915357 | 0.81 | SLC16A3 (0.46) | SLC16A3SLC16A1MCTS1 | |
| SCHEMBL29915313 | 0.80 | MAPT (0.40) | SLC16A3SLC16A1MCTS1SMN1; SMN2MEN1 | |
| SCHEMBL22613715 | 0.78 | FAAH (0.51) | SLC16A3SLC16A1MCTS1DYRK1ACLK4 | |
| SCHEMBL20600251 | 0.75 | PTGDR (0.44) | DYRK1ACLK4PTGDRALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11440922-B2 | Heterocyclylmethylidene derivatives and their use as modulators of mGluR5 receptors | Recordati Industria Chimica e Farmacentica S.p.A. (IT) | 2022-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11440922-B2 | Heterocyclylmethylidene derivatives and their use as modulators of mGluR5 receptors | GRM5, GRIK5, GRM2 | SLC16A3 1146/4885SLC16A1 778/4885MCTS1 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.