Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 1.00 |
| ▸ | PDGFRB | P09619 | 5/20 | 1.00 |
| ▸ | KIT | P10721 | 10/20 | 0.72 |
| ▸ | FLT3 | P36888 | 10/20 | 0.72 |
| ▸ | CSF1R | P07333 | 7/20 | 0.72 |
| ▸ | FLT1 | P17948 | 7/20 | 0.72 |
| ▸ | FLT4 | P35916 | 7/20 | 0.72 |
| ▸ | LCK | P06239 | 5/20 | 0.72 |
| ▸ | LYN | P07948 | 5/20 | 0.72 |
| ▸ | SRC | P12931 | 5/20 | 0.72 |
| ▸ | BLK | P51451 | 5/20 | 0.72 |
| ▸ | FYN | P06241 | 4/20 | 0.72 |
| ▸ | ABL1 | P00519 | 2/20 | 0.72 |
| ▸ | PLK4 | O00444 | 3/20 | 0.59 |
| ▸ | AURKA | O14965 | 3/20 | 0.59 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.59 |
| ▸ | PRKACA | P17612 | 3/20 | 0.59 |
| ▸ | RPS6KB1 | P23443 | 3/20 | 0.59 |
| ▸ | CSNK1D | P48730 | 3/20 | 0.59 |
| ▸ | STK3 | Q13188 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17929411 | 1.00 | KDR (1.00) | KDRPDGFRBKITFLT3CSF1R | |
| SCHEMBL17929412 | 0.89 | KDR (0.80) | KDRPDGFRBKITFLT3CSF1R | |
| SCHEMBL17929413 | 0.86 | KDR (1.00) | KDRPDGFRBKITFLT3CSF1R | |
| SCHEMBL29918230 | 0.86 | KDR (1.00) | KDRPDGFRBKITFLT3CSF1R | |
| SCHEMBL233874 | 0.84 | KDR (1.00) | KDRPDGFRBKITFLT3CSF1R | |
| SCHEMBL18559447 | 0.79 | KDR (0.70) | KDRPDGFRBKITFLT3CSF1R | |
| SCHEMBL23558924 | 0.77 | KDR (0.63) | KDRPDGFRBKITFLT3CSF1R | |
| SCHEMBL16303676 | 0.77 | KDR (0.80) | KDRPDGFRBKITFLT3CSF1R | |
| SCHEMBL425226 | 0.76 | KDR (0.80) | KDRPDGFRBKITFLT3CSF1R | |
| SCHEMBL422392 | 0.75 | KDR (0.86) | KDRKITFLT3CSF1RFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115068620-A | Pharmaceutical composition capable of reducing generation of arylamine impurities | 天津睿创康泰生物技术有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-115068620-A | Pharmaceutical composition capable of reducing generation of arylamine impurities | 天津睿创康泰生物技术有限公司 | 2022-09-20 | — | — | CN | disclosed |