Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 7/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 6/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23535555 | 1.00 | MTNR1A (0.40) | MTNR1AMTNR1BMPOTSHRHTR2A | |
| SCHEMBL31672697 | 0.86 | MTNR1A (0.39) | MTNR1AMTNR1BMPOTSHRHTR2A | |
| SCHEMBL14960971 | 0.81 | MTNR1A (0.41) | MTNR1AMTNR1BMPOHTR2AHTR1A | |
| SCHEMBL14961107 | 0.80 | MTNR1A (0.43) | MTNR1AMTNR1BMPOTSHRHTR2A | |
| SCHEMBL29854552 | 0.79 | HASPIN (0.39) | MTNR1AMTNR1BHTR2AGPR84TRPM8 | |
| SCHEMBL23295489 | 0.79 | HASPIN (0.39) | MTNR1AMTNR1BHTR2AGPR84TRPM8 | |
| SCHEMBL22643887 | 0.78 | MTNR1A (0.39) | MTNR1AMTNR1BMPOHTR2AGPR84 | |
| SCHEMBL14961101 | 0.76 | MTNR1A (0.49) | MTNR1AMTNR1BMPOHTR2AHTR1A | |
| SCHEMBL14960990 | 0.72 | HTR1B (0.46) | MTNR1AMTNR1BMPOHTR2AHTR1A | |
| SCHEMBL23295297 | 0.71 | MAPT (0.38) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120025336-A | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-05-23 | — | — | CN | disclosed |
| CN-115087657-B | LIN28 inhibitors and methods of use thereof | 加利福尼亚大学董事会 | 2025-01-21 | — | — | CN | disclosed |
| EP-4077332-A1 | INHIBITORS OF LIN28 AND METHODS OF USE THEREOF | The Regents of the University of California (US) | 2022-10-26 | — | — | EP | disclosed |
| CN-115087657-A | LIN28 inhibitor and method of use thereof | 加利福尼亚大学董事会 | 2022-09-20 | — | — | CN | disclosed |