Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 15/20 | 0.43 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29920312 | 1.00 | TRPV1 (0.43) | TRPV1CFTRCYP3A4KCNE1KCNQ1 | |
| SCHEMBL29920568 | 0.85 | PSEN1 (0.35) | TRPV1CFTRKCNE1KCNQ1 | |
| SCHEMBL29920475 | 0.85 | PSEN1 (0.35) | TRPV1CFTRKCNE1KCNQ1 | |
| SCHEMBL29920313 | 0.85 | PSEN1 (0.35) | TRPV1CFTRKCNE1KCNQ1 | |
| SCHEMBL29920674 | 0.84 | TRPV1 (0.34) | TRPV1KCNE1KCNQ1 | |
| SCHEMBL29920373 | 0.82 | TRPV1 (0.38) | TRPV1KCNE1KCNQ1 | |
| SCHEMBL29920748 | 0.82 | TRPV1 (0.38) | TRPV1KCNE1KCNQ1 | |
| SCHEMBL28001848 | 0.78 | TRPV1 (0.46) | TRPV1CFTRCYP3A4CYP2D6 | |
| SCHEMBL29920650 | 0.77 | TRPV1 (0.50) | TRPV1CFTRCYP3A4CYP2D6 | |
| SCHEMBL29920431 | 0.76 | TRPV1 (0.41) | TRPV1CFTRCYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022217248-A1 | SUBSTITUTED SULFONAMIDE-CHROMAN COMPOUNDS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |