Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 19/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23423231 | 0.79 | CFTR (0.51) | TRPV1CFTRCYP3A4CYP2D6 | |
| SCHEMBL2318940 | 0.78 | CFTR (0.61) | TRPV1CFTRCYP3A4CYP2D6 | |
| SCHEMBL29920312 | 0.77 | TRPV1 (0.43) | TRPV1CFTRCYP3A4CYP2D6 | |
| SCHEMBL29920334 | 0.77 | TRPV1 (0.43) | TRPV1CFTRCYP3A4CYP2D6 | |
| SCHEMBL29920431 | 0.76 | TRPV1 (0.41) | TRPV1CFTRCYP3A4CYP2D6 | |
| SCHEMBL29920363 | 0.76 | TRPV1 (0.41) | TRPV1CFTRCYP3A4CYP2D6 | |
| SCHEMBL6559589 | 0.76 | TRPV1 (0.52) | TRPV1CFTRCYP3A4 | |
| SCHEMBL29920490 | 0.76 | TRPV1 (0.41) | TRPV1CFTRCYP3A4CYP2D6 | |
| SCHEMBL10589903 | 0.76 | PSEN1 (0.46) | TRPV1CFTRCYP3A4 | |
| SCHEMBL6560815 | 0.75 | TRPV1 (0.48) | TRPV1CFTRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022217248-A1 | SUBSTITUTED SULFONAMIDE-CHROMAN COMPOUNDS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |