Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29920352 | 1.00 | MAOB (0.41) | MAOBCA1CA2CA7CA9 | |
| SCHEMBL3183702 | 0.87 | FABP6 (0.46) | CA1CA2CA7CA9MALT1 | |
| SCHEMBL30251200 | 0.80 | MAOB (0.50) | MAOBCA1CA2CA7CA9 | |
| SCHEMBL25526149 | 0.80 | MAOB (0.41) | MAOBCA1CA2CA7CA9 | |
| SCHEMBL29640600 | 0.80 | PBRM1 (0.40) | CA1CA2CA7CA9MALT1 | |
| SCHEMBL1500180 | 0.80 | MAOB (0.50) | MAOBCA1CA2CA7CA9 | |
| SCHEMBL3456628 | 0.80 | PBRM1 (0.40) | CA1CA2CA7CA9MALT1 | |
| SCHEMBL1500280 | 0.78 | CYP19A1 (0.48) | MAOBCA1CA2CA7CA9 | |
| SCHEMBL31525604 | 0.78 | CYP19A1 (0.48) | MAOBCA1CA2CA7CA9 | |
| SCHEMBL29448029 | 0.75 | PKM (0.47) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022217248-A1 | SUBSTITUTED SULFONAMIDE-CHROMAN COMPOUNDS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |