Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 5/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19658610 | 0.76 | ADRA2A (0.42) | ADRA2AKDM4CTRPV1NTRK1KDM6B | |
| SCHEMBL29920817 | 0.73 | ADRA2A (0.47) | ADRA2AKDM4CTRPV1NTRK1MAPK1 | |
| SCHEMBL19652243 | 0.73 | DPP4 (0.41) | ADRA2AKDM4CTRPV1NTRK1KDM6B | |
| SCHEMBL24593571 | 0.70 | ADRA2A (0.50) | ADRA2AKDM4CTRPV1NTRK1MAP3K14 | |
| SCHEMBL12651543 | 0.70 | ADRA2A (0.50) | ADRA2AKDM4CTRPV1NTRK1MAP3K14 | |
| SCHEMBL12828517 | 0.70 | ADRA2A (0.50) | ADRA2AKDM4CTRPV1NTRK1MAP3K14 | |
| SCHEMBL3555891 | 0.70 | ADRA2A (0.50) | ADRA2AKDM4CTRPV1MAP3K14SLC6A4 | |
| SCHEMBL29920509 | 0.70 | ADRA2A (0.38) | ADRA2AKDM4CTRPV1NTRK1KDM6B | |
| SCHEMBL27830379 | 0.70 | ADRA2A (0.47) | ADRA2AKDM4CTRPV1NTRK1MAP3K14 | |
| SCHEMBL1569667 | 0.68 | KDM4C (0.43) | ADRA2AKDM4CTRPV1NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022217248-A1 | SUBSTITUTED SULFONAMIDE-CHROMAN COMPOUNDS, AND PHARMACEUTICAL COMPOSITIONS, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |