Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | CDC7 | O00311 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 2/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | BCL2 | P10415 | 1/20 | 0.32 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29922370 | 0.94 | POLB (0.34) | ESR2POLBACHECDC7PIM1 | |
| SCHEMBL30476244 | 0.79 | SCD (0.39) | ACHEPIM1DRD2SLC6A4 | |
| SCHEMBL29922376 | 0.75 | DRD2 (0.38) | ACHEDRD2SLC6A4CYP17A1 | |
| SCHEMBL17824559 | 0.72 | PRMT5 (0.45) | POLBCDC7PIM1CSNK2BCSNK2A1 | |
| SCHEMBL3523366 | 0.70 | MAPK14 (0.47) | ACHECDC7PIM1CSNK2BCSNK2A1 | |
| SCHEMBL24469239 | 0.69 | POLB (0.36) | POLBPIM1SLC6A4 | |
| SCHEMBL29426504 | 0.69 | PRMT5 (0.42) | POLBCDC7PIM1CSNK2BCSNK2A1 | |
| SCHEMBL24076263 | 0.69 | PRMT5 (0.42) | POLBCDC7PIM1CSNK2BCSNK2A1 | |
| SCHEMBL17824774 | 0.67 | PRMT5 (0.46) | CDC7PIM1CSNK2BCSNK2A1 | |
| SCHEMBL15159992 | 0.66 | ESR2 (0.59) | ESR2POLBPIM1CSNK2A1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188735-A1 | HETEROCYCLIC COMPOUNDS AS HPK1 INHIBITORS | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2022-09-15 | — | — | WO | disclosed |