Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29922328 | 0.86 | HSD17B10 (0.44) | HSD17B10NPC1ALDH1A1MAPTHPGD | |
| SCHEMBL13836668 | 0.81 | NPC1 (0.71) | HSD17B10NPC1ALDH1A1TP53MAPT | |
| SCHEMBL1104824 | 0.80 | ALDH1A1 (0.68) | HSD17B10NPC1ALDH1A1THRBHTT | |
| SCHEMBL23418617 | 0.78 | NPC1 (0.59) | HSD17B10NPC1ALDH1A1MAPTTHRB | |
| SCHEMBL29922395 | 0.77 | NPC1 (0.65) | HSD17B10NPC1ALDH1A1TP53MAPT | |
| SCHEMBL29784251 | 0.77 | HSD17B10 (1.00) | HSD17B10NPC1ALDH1A1THRBHTT | |
| SCHEMBL120600 | 0.77 | HSD17B10 (1.00) | HSD17B10NPC1ALDH1A1THRBHTT | |
| SCHEMBL3065613 | 0.76 | HSD17B10 (0.82) | HSD17B10NPC1ALDH1A1TP53MAPT | |
| SCHEMBL541343 | 0.75 | HSD17B10 (0.76) | HSD17B10NPC1ALDH1A1TP53MAPT | |
| SCHEMBL28588099 | 0.74 | ALDH1A1 (0.59) | HSD17B10NPC1ALDH1A1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112830897-B | Ureido-containing benzimidazole derivative and preparation method and application thereof | 石家庄以岭药业股份有限公司 | 2022-09-09 | — | — | CN | disclosed |