Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 7/20 | 0.43 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 2/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22057308 | 0.83 | NPY5R (0.45) | NPY5RAVPR1AAKR1A1AKR1B1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL6820680 | 0.82 | NPY5R (0.44) | NPY5RAVPR1AAKR1A1AKR1B1SIGMAR1 | |
| SCHEMBL29922416 | 0.81 | POLB (0.40) | AVPR1AKMT2ASIGMAR1MAPT | |
| SCHEMBL4367569 | 0.81 | AVPR1A (0.48) | NPY5RAVPR1AAKR1B1SIGMAR1 | |
| SCHEMBL18854250 | 0.78 | SIGMAR1 (0.55) | NPY5RAVPR1ASIGMAR1 | |
| SCHEMBL4372121 | 0.77 | NPY5R (0.46) | NPY5RAVPR1ASIGMAR1 | |
| SCHEMBL29922152 | 0.76 | CA1 (0.38) | AVPR1ASIGMAR1 | |
| SCHEMBL2361177 | 0.74 | SIGMAR1 (0.73) | SIGMAR1 | |
| SCHEMBL6270334 | 0.74 | SLC6A4 (0.46) | NPY5RAVPR1AKMT2A | |
| SCHEMBL31394077 | 0.72 | AVPR1A (0.51) | NPY5RAVPR1ASIGMAR1MAPTMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022188735-A1 | HETEROCYCLIC COMPOUNDS AS HPK1 INHIBITORS | GUANGDONG NEWOPP BIOPHARMACEUTICALS CO., LTD. (CN) | 2022-09-15 | — | — | WO | disclosed |