Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | CCKBR | P32239 | 4/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.52 |
| ▸ | DDB1 | Q16531 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19370808 | 1.00 | MEN1 (0.59) | MEN1MAPTKMT2AALDH1A1NPC1 | |
| SCHEMBL19359484 | 1.00 | MEN1 (0.59) | MEN1MAPTKMT2AALDH1A1NPC1 | |
| SCHEMBL21965737 | 0.83 | DDB1 (0.67) | CRBNDDB1TSHR | |
| SCHEMBL23874550 | 0.81 | CRBN (0.66) | MEN1KMT2ARAB9AEPHX2CRBN | |
| SCHEMBL20811941 | 0.81 | CRBN (0.69) | MEN1KMT2AALDH1A1CRBNDDB1 | |
| SCHEMBL19370726 | 0.79 | NPC1 (0.58) | MEN1MAPTKMT2AALDH1A1NPC1 | |
| SCHEMBL8904435 | 0.77 | MAPT (0.53) | MEN1MAPTKMT2AALDH1A1NPC1 | |
| SCHEMBL8904206 | 0.77 | MAPT (0.53) | MEN1MAPTKMT2AALDH1A1NPC1 | |
| SCHEMBL8904208 | 0.77 | MAPT (0.53) | MEN1MAPTKMT2AALDH1A1NPC1 | |
| SCHEMBL4893387 | 0.74 | TP53 (0.87) | MEN1MAPTKMT2AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153644-B | Small molecules against CEREBLON to enhance effector T cell function | H·李·莫菲特癌症中心研究有限公司 | 2022-10-21 | — | — | CN | disclosed |