Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.87 |
| ▸ | TSHR | P16473 | 1/20 | 0.87 |
| ▸ | RAB9A | P51151 | 9/20 | 0.79 |
| ▸ | NPC1 | O15118 | 7/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.79 |
| ▸ | MITF | O75030 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 8/20 | 0.74 |
| ▸ | MEN1 | O00255 | 6/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.74 |
| ▸ | HTT | P42858 | 4/20 | 0.74 |
| ▸ | LMNA | P02545 | 1/20 | 0.74 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.74 |
| ▸ | STAT1 | P42224 | 1/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.72 |
| ▸ | GAA | P10253 | 1/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | CASP3 | P42574 | 1/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31040569 | 1.00 | TP53 (0.87) | TP53TSHRRAB9ANPC1ALDH1A1 | |
| SCHEMBL17084260 | 0.98 | TP53 (0.84) | TP53TSHRRAB9ANPC1ALDH1A1 | |
| SCHEMBL14442613 | 0.95 | TP53 (0.84) | TP53TSHRRAB9ANPC1ALDH1A1 | |
| SCHEMBL22103808 | 0.92 | TP53 (0.74) | TP53TSHRRAB9ANPC1ALDH1A1 | |
| SCHEMBL6388689 | 0.91 | TP53 (0.73) | TP53TSHRRAB9ANPC1ALDH1A1 | |
| SCHEMBL7610775 | 0.91 | TP53 (0.73) | TP53TSHRRAB9ANPC1ALDH1A1 | |
| SCHEMBL25002342 | 0.90 | MAPT (0.73) | TP53TSHRRAB9ANPC1ALDH1A1 | |
| SCHEMBL21750961 | 0.90 | TSHR (0.82) | TP53TSHRRAB9ANPC1ALDH1A1 | |
| SCHEMBL22103791 | 0.90 | TSHR (0.82) | TP53TSHRRAB9ANPC1ALDH1A1 | |
| SCHEMBL5852120 | 0.90 | TP53 (0.82) | TP53TSHRRAB9ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080249075-A1 | C11 Modified Retrosteroids as Progesterone Receptor Modulator Compounds | SOLVAY PHARMACEUTICALS GMBH (DE) | 2008-10-09 | — | — | US | disclosed |
| US-7169815-B2 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2007-01-30 | — | — | US | disclosed |
| US-20030204113-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2003-10-30 | — | — | US | disclosed |
| US-6586628-B2 | Oxidation resistance | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2003-07-01 | — | — | US | disclosed |
| US-20020147365-A1 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | THE FANNING CORPORATION | 2002-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020147365-A1 | 3-methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | TP53 4572/4885TSHR 1399/4885RAB9A 2530/4885 |
| US-20030204113-A1 | 3-Methoxybenzyl thiourea derivatives and improved lipid compositions containing same | GPX4, LIPC, GPX1 | TP53 4572/4885TSHR 1399/4885RAB9A 2530/4885 |
| US-20080249075-A1 | C11 Modified Retrosteroids as Progesterone Receptor Modulator Compounds | HSD17B11, CYP19A1, ESRRA | TP53 4505/4885TSHR 240/4885RAB9A 1020/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.