Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.51 |
| ▸ | CYP17A1 | P05093 | 6/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1526883 | 1.00 | PLAU (0.55) | PLAUDYRK1ACYP17A1CYP11B1CYP11B2 | |
| SCHEMBL303915 | 0.86 | DYRK1A (0.55) | PLAUDYRK1ACYP3A4CCR1CCR5 | |
| SCHEMBL13409731 | 0.81 | LMNA (0.40) | PLAUCYP3A4ALDH1A1LMNAKDM4E | |
| SCHEMBL1871112 | 0.81 | CYP3A4 (0.42) | PLAUDYRK1ACYP17A1CYP11B1CYP11B2 | |
| SCHEMBL129972 | 0.80 | PLAU (0.56) | PLAUDYRK1ACYP3A4CCR1CCR5 | |
| SCHEMBL31521713 | 0.80 | PLAU (0.56) | PLAUDYRK1ACYP3A4CCR1CCR5 | |
| SCHEMBL1834564 | 0.79 | PLAU (0.59) | PLAUDYRK1ACCR1CCR5CCR8 | |
| SCHEMBL12055259 | 0.79 | PLAU (0.59) | PLAUCYP17A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL21951884 | 0.79 | PLAU (0.55) | PLAUCYP17A1CYP11B1CYP11B2CYP3A4 | |
| SCHEMBL28068060 | 0.79 | PLAU (0.55) | PLAUCYP17A1CYP11B1CYP11B2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598533-A1 | LACTATE ENHANCING COMPOUNDS AND USES THEREOF | Gliapharm SA (CH) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024074436-A1 | LACTATE ENHANCING COMPOUNDS AND USES THEREOF | GLIAPHARM SA (CH) | 2024-04-11 | — | — | WO | disclosed |
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |