Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 6/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD1 | P21728 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD5 | P21918 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 2/20 | 0.47 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19359233 | 1.00 | CRBN (0.63) | CRBNRAB9ADRD2DRD1DRD4 | |
| SCHEMBL19359372 | 0.89 | CRBN (0.73) | CRBNRAB9ADRD2DRD4ALDH1A1 | |
| SCHEMBL29923644 | 0.88 | CRBN (0.83) | CRBNSLC18A3ALDH1A1DDB1TDP1 | |
| SCHEMBL19359391 | 0.88 | CRBN (0.83) | CRBNSLC18A3ALDH1A1DDB1TDP1 | |
| SCHEMBL9631384 | 0.81 | CRBN (0.67) | CRBNRAB9ADRD2DRD1DRD4 | |
| SCHEMBL25834117 | 0.80 | CRBN (0.61) | CRBNDRD2DRD1DRD4DRD5 | |
| SCHEMBL6178113 | 0.78 | CRBN (1.00) | CRBNALDH1A1DDB1TDP1CHRM2 | |
| SCHEMBL6180704 | 0.78 | CRBN (1.00) | CRBNALDH1A1DDB1TDP1CHRM2 | |
| SCHEMBL29943635 | 0.78 | CRBN (1.00) | CRBNALDH1A1DDB1TDP1CHRM2 | |
| SCHEMBL1499656 | 0.78 | CRBN (1.00) | CRBNALDH1A1DDB1TDP1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109153644-B | Small molecules against CEREBLON to enhance effector T cell function | H·李·莫菲特癌症中心研究有限公司 | 2022-10-21 | — | — | CN | disclosed |