Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 6/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD4 | P21917 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19359372 | 0.91 | CRBN (0.73) | CRBNRAB9ADDB1ALDH1A1DRD2 | |
| SCHEMBL29923307 | 0.81 | CRBN (0.63) | CRBNRAB9ADDB1ALDH1A1DRD2 | |
| SCHEMBL19359233 | 0.81 | CRBN (0.63) | CRBNRAB9ADDB1ALDH1A1DRD2 | |
| SCHEMBL6180704 | 0.80 | CRBN (1.00) | CRBNDDB1ALDH1A1TDP1CHRM2 | |
| SCHEMBL1499656 | 0.80 | CRBN (1.00) | CRBNDDB1ALDH1A1TDP1CHRM2 | |
| SCHEMBL6178113 | 0.80 | CRBN (1.00) | CRBNDDB1ALDH1A1TDP1CHRM2 | |
| SCHEMBL29943635 | 0.80 | CRBN (1.00) | CRBNDDB1ALDH1A1TDP1CHRM2 | |
| SCHEMBL7400226 | 0.76 | CRBN (0.54) | CRBNRAB9ADDB1ALDH1A1TDP1 | |
| SCHEMBL3321300 | 0.76 | ALDH1A1 (0.52) | CRBNRAB9AALDH1A1TSHRHTT | |
| SCHEMBL1358007 | 0.73 | CRBN (0.58) | CRBNDDB1ALDH1A1TDP1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079249-A | Serotine antagonists at 5-HT2 level, antiallergens, antihistamines | ADIR ET COMPAGNIE (FR) | 1992-01-07 | — | — | US | disclosed |
| US-5071847-A | BIS (ARYL) ALKENE COMPOUNDS OF HOMOPIPERIDINES USEFUL AS SEROTONIN-ANTAGONISTS | ADIR ET COMPAGNIE (FR) | 1991-12-10 | — | — | US | disclosed |
| US-4943577-A | PSYCHOLOGICAL DISORDERS | ADIR ET CIE (FR) | 1990-07-24 | — | — | US | disclosed |
| US-4877788-A | ANXIOLYTIC, ANTIAGGRESSIVE OR ANTIPSYCHOTIC AGENT | ADIR ET CIE (FR) | 1989-10-31 | — | — | US | disclosed |