Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 10/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27214570 | 1.00 | KDM4C (0.41) | KDM4CMAPTGPBAR1KDM6BPTGDR2 | |
| SCHEMBL29923235 | 0.90 | KDM4C (0.36) | KDM4CKDM6B | |
| SCHEMBL27214539 | 0.90 | KDM4C (0.36) | KDM4CKDM6B | |
| SCHEMBL29923145 | 0.86 | GPR119 (0.37) | KDM4CKDM6B | |
| SCHEMBL29923339 | 0.86 | GPR119 (0.37) | KDM4CKDM6B | |
| SCHEMBL27231219 | 0.86 | BRD4 (0.34) | KDM4CROCK2BUB1 | |
| SCHEMBL27214554 | 0.86 | BRD4 (0.34) | KDM4CROCK2BUB1 | |
| SCHEMBL27214590 | 0.86 | BRD4 (0.34) | KDM4CROCK2BUB1 | |
| SCHEMBL29923543 | 0.84 | KDM4C (0.34) | KDM4CKDM6B | |
| SCHEMBL27231197 | 0.84 | KDM4C (0.34) | KDM4CKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022217232-A1 | CHROMANS AND BENZOFURANS AS 5-HT1A AND TAAR1 AGONISTS | SUNOVION PHARMACEUTICALS INC. (US) | 2022-10-13 | — | — | WO | disclosed |