Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 2/20 | 0.35 |
| ▸ | CASP6 | P55212 | 2/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915807 | 1.00 | KDM4E (0.38) | KDM4EALOX12HTTNPC1RAB9A | |
| SCHEMBL24916137 | 0.87 | NSD2 (0.38) | KDM4EHTTRAB9AMAPTSMN1; SMN2 | |
| SCHEMBL29923321 | 0.87 | NSD2 (0.38) | KDM4EHTTRAB9AMAPTSMN1; SMN2 | |
| SCHEMBL29923413 | 0.85 | CYP19A1 (0.38) | KDM4EALOX12HTTRAB9AMAPT | |
| SCHEMBL24916306 | 0.85 | CYP19A1 (0.38) | KDM4EALOX12HTTRAB9AMAPT | |
| SCHEMBL24916107 | 0.84 | KDM4E (0.38) | KDM4EL3MBTL1NSD2CASP6CCR1 | |
| SCHEMBL29923797 | 0.84 | KDM4E (0.38) | KDM4EL3MBTL1NSD2CASP6CCR1 | |
| SCHEMBL24916497 | 0.82 | KDM4E (0.41) | KDM4EHTTL3MBTL1NSD2CASP6 | |
| SCHEMBL24915832 | 0.81 | KDM4E (0.38) | KDM4EALOX12HTTNPC1RAB9A | |
| SCHEMBL29923777 | 0.81 | KDM4E (0.38) | KDM4EALOX12HTTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |