Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PRNP | P04156 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | NQO2 | P16083 | 4/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24916334 | 1.00 | MAPT (0.46) | MAPTALDH1A1PRNPNPSR1RXFP1 | |
| SCHEMBL27901375 | 0.82 | PSMB5 (0.50) | MAPTALDH1A1PRNPNPSR1RXFP1 | |
| SCHEMBL31353452 | 0.80 | PRKDC (0.39) | MAPTALDH1A1NQO2PDE3BPDE3A | |
| SCHEMBL31353408 | 0.80 | KDM4E (0.40) | ALDH1A1NPSR1RXFP1NQO2PDE3B | |
| SCHEMBL24915779 | 0.78 | MAPT (0.45) | MAPTALDH1A1PRNPNPSR1RXFP1 | |
| SCHEMBL29923988 | 0.78 | MAPT (0.45) | MAPTALDH1A1PRNPNPSR1RXFP1 | |
| SCHEMBL24915598 | 0.77 | PDE3B (0.40) | MAPTALDH1A1PRNPNPSR1RXFP1 | |
| SCHEMBL31353367 | 0.75 | EPAS1 (0.34) | PSMB5 | |
| SCHEMBL31353603 | 0.75 | HPGD (0.43) | MAPTALDH1A1PRNPNPSR1NQO2 | |
| SCHEMBL23208763 | 0.72 | RXFP1 (0.46) | MAPTALDH1A1PRNPNPSR1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121586713-A | Quinoline derivatives and pharmaceutical compositions thereof for the treatment of diseases | 百济神州(苏州)生物科技有限公司 | 2026-02-27 | — | — | CN | disclosed |
| WO-2025021217-A1 | QUINOLINE DERIVATIVES AND PHARMARCEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF DISEASE | BEIGENE SWITZERLAND GMBH (CH) | 2025-01-30 | — | — | WO | disclosed |
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |