Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2998324 | 1.00 | SRC (0.45) | SRCLMNAKDM4EMAPTGRM1 | |
| SCHEMBL3828983 | 0.92 | KDM4E (0.42) | SRCLMNAKDM4EMAPTGRM1 | |
| SCHEMBL21947678 | 0.87 | SRC (0.45) | SRCLMNAKDM4EMAPTEGFR | |
| SCHEMBL440060 | 0.81 | BCHE (0.50) | SRCLMNAKDM4EMAPTHTR1A | |
| SCHEMBL3247140 | 0.81 | KDM4E (0.48) | SRCLMNAKDM4EMAPTGRM1 | |
| SCHEMBL5185398 | 0.81 | SRC (0.45) | SRCLMNAKDM4EMAPTGRM1 | |
| SCHEMBL29393432 | 0.81 | KDM4E (0.46) | LMNAKDM4EMAPTGRM1EGFR | |
| SCHEMBL2949117 | 0.81 | KDM4E (0.46) | LMNAKDM4EMAPTGRM1EGFR | |
| SCHEMBL2946799 | 0.81 | LMNA (0.43) | LMNAKDM4EMAPTGRM1EGFR | |
| SCHEMBL31384368 | 0.81 | LMNA (0.43) | SRCLMNAKDM4EMAPTGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |