Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PRKDC | P78527 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.32 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
| ▸ | CA9 | Q16790 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL304092 | 0.84 | ERN1 (0.41) | ALDH1A1KDM4EERN1LMNAMAPT | |
| SCHEMBL18553998 | 0.78 | ERN1 (0.42) | ALDH1A1ERN1PRKDCCYP3A4CA1 | |
| SCHEMBL21130264 | 0.75 | ALDH1A1 (0.37) | ALDH1A1KDM4EERN1LMNAMAPT | |
| SCHEMBL12581708 | 0.75 | CYP3A4 (0.46) | ALDH1A1ERN1MAPTPRKDCCYP3A4 | |
| SCHEMBL31189003 | 0.75 | MEN1 (0.37) | ALDH1A1KDM4EERN1LMNAMAPT | |
| SCHEMBL16207565 | 0.75 | ERN1 (0.34) | ALDH1A1ERN1LMNAMAPTPRKDC | |
| SCHEMBL31353446 | 0.75 | CA1 (0.33) | ERN1LMNAGAAPRKDCCA1 | |
| SCHEMBL12581710 | 0.72 | PRKDC (0.53) | ALDH1A1KDM4EERN1LMNAMAPT | |
| SCHEMBL31426082 | 0.72 | ERN1 (0.33) | ALDH1A1ERN1LMNAMAPTPRKDC | |
| SCHEMBL22060773 | 0.71 | CYP3A4 (0.36) | ALDH1A1ERN1MAPTPRKDCCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334305-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022236101-A1 | WDR5 INHIBITORS AND MODULATORS | VANDERBILT UNIVERSITY (US) | 2022-11-10 | — | — | WO | disclosed |
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |