Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663614 | 1.00 | TRIM24 (0.46) | TRIM24TYRTRIM33ERN1KDM4E | |
| SCHEMBL29589363 | 0.86 | TLR8 (0.43) | TRIM24TYRTRIM33ERN1KDM4E | |
| SCHEMBL1666537 | 0.86 | TLR8 (0.43) | TRIM24TYRTRIM33ERN1KDM4E | |
| SCHEMBL1663396 | 0.79 | CNR1 (0.43) | KDM4EALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL29923830 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL24915825 | 0.79 | KDM4E (0.41) | KDM4EALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL11195737 | 0.77 | KDM4E (0.52) | KDM4EALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL24916024 | 0.77 | CNR1 (0.41) | KDM4EALDH1A1LMNAPOLBHSD17B10 | |
| SCHEMBL2206398 | 0.75 | PDE10A (0.54) | CYP1A2 | |
| SCHEMBL11192735 | 0.75 | RIPK2 (0.49) | TRIM24TYRTRIM33KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |