Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NQO2 | P16083 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24915825 | 1.00 | KDM4E (0.41) | KDM4ELMNAPOLBMEN1ALDH1A1 | |
| SCHEMBL1663396 | 0.79 | CNR1 (0.43) | KDM4ELMNAPOLBMEN1ALDH1A1 | |
| SCHEMBL1663614 | 0.79 | TRIM24 (0.46) | KDM4ELMNAPOLBMEN1ALDH1A1 | |
| SCHEMBL29923693 | 0.79 | TRIM24 (0.46) | KDM4ELMNAPOLBMEN1ALDH1A1 | |
| SCHEMBL11195737 | 0.77 | KDM4E (0.52) | KDM4ELMNAPOLBMEN1ALDH1A1 | |
| SCHEMBL24916024 | 0.77 | CNR1 (0.41) | KDM4ELMNAPOLBMEN1ALDH1A1 | |
| SCHEMBL2209746 | 0.75 | PDE10A (0.50) | ALDH1A1CYP1A2 | |
| SCHEMBL31467684 | 0.75 | PDE10A (0.50) | ALDH1A1CYP1A2 | |
| SCHEMBL29923390 | 0.74 | LMNA (0.58) | KDM4ELMNAEGFRMAPTCYP1A2 | |
| SCHEMBL590225 | 0.74 | LMNA (0.58) | KDM4ELMNAEGFRMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |