Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 3/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5262975 | 1.00 | PDGFRB (0.42) | PDGFRBPDGFRAKDM4EALDH1A1CYP3A4 | |
| SCHEMBL29923648 | 0.83 | NSD2 (0.41) | KDM4EALDH1A1HPGDMEN1CYP1A2 | |
| SCHEMBL17502531 | 0.83 | NSD2 (0.41) | KDM4EALDH1A1HPGDMEN1CYP1A2 | |
| SCHEMBL17502532 | 0.83 | NSD2 (0.40) | CYP3A4CYP1A2CYP2C19NSD2CASP6 | |
| SCHEMBL20292984 | 0.82 | NSD2 (0.40) | ALDH1A1CYP3A4MEN1CYP1A2MAPT | |
| SCHEMBL3375901 | 0.82 | CCR1 (0.38) | KDM4EALDH1A1CYP3A4HSD17B10MEN1 | |
| SCHEMBL10290496 | 0.81 | NSD2 (0.50) | PDGFRBPDGFRAKDM4EALDH1A1CYP3A4 | |
| SCHEMBL11769024 | 0.80 | PDE10A (0.40) | PDGFRBPDGFRAKDM4EALDH1A1CYP3A4 | |
| SCHEMBL9073416 | 0.80 | HSP90AA1 (0.50) | PDGFRBPDGFRAKDM4EALDH1A1CYP3A4 | |
| SCHEMBL9073161 | 0.80 | NOS3 (0.41) | PDGFRBPDGFRAKDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |