Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19407560 | 0.78 | MAPT (0.56) | KMT2AMEN1HPGDNPC1RAB9A | |
| SCHEMBL7698230 | 0.78 | KMT2A (0.68) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL19385987 | 0.76 | HTT (0.55) | KMT2AMEN1HPGDCYP1A2ALDH1A1 | |
| SCHEMBL29858122 | 0.76 | HTT (0.55) | KMT2AMEN1HPGDCYP1A2ALDH1A1 | |
| SCHEMBL2225530 | 0.75 | NPC1 (0.56) | KMT2AMEN1HPGDSMN1; SMN2NPC1 | |
| SCHEMBL10674362 | 0.72 | KDM4E (0.67) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL3461357 | 0.72 | SMN1; SMN2 (0.54) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL28335503 | 0.72 | CYP1A2 (0.62) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL28105710 | 0.72 | SMN1; SMN2 (0.61) | KMT2AMEN1HPGDLMNASMN1; SMN2 | |
| SCHEMBL3462627 | 0.71 | SMN1; SMN2 (0.64) | KMT2AMEN1HPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4055013-A1 | WDR5 INHIBITORS AND MODULATORS | Vanderbilt University (US) | 2022-09-14 | — | — | EP | disclosed |