Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 8/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22730011 | 1.00 | IDO1 (0.58) | IDO1LNPEPUSP30TLR8TLR7 | |
| SCHEMBL21213954 | 1.00 | IDO1 (0.58) | IDO1LNPEPUSP30TLR8TLR7 | |
| SCHEMBL29923884 | 1.00 | IDO1 (0.58) | IDO1LNPEPUSP30TLR8TLR7 | |
| SCHEMBL17729982 | 1.00 | IDO1 (0.58) | IDO1LNPEPUSP30TLR8TLR7 | |
| Bicarbonate SCHEMBL9280862 | 0.85 | IDO1 (0.54) | IDO1LNPEPUSP30TLR8TLR7 | |
| SCHEMBL17729954 | 0.84 | IDO1 (0.54) | IDO1LNPEPUSP30TLR8TLR7 | |
| SCHEMBL30209423 | 0.84 | IDO1 (0.54) | IDO1LNPEPUSP30TLR8TLR7 | |
| SCHEMBL28335167 | 0.84 | IDO1 (0.45) | IDO1LNPEPUSP30TLR8TLR7 | |
| SCHEMBL28335166 | 0.84 | IDO1 (0.45) | IDO1LNPEPUSP30TLR8TLR7 | |
| SCHEMBL19900796 | 0.82 | HDAC4 (0.49) | IDO1LNPEPTLR8TLR7BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110092750-B | Pentafluoro sulfanyl substituted amide compound, preparation method and application thereof in medicine | 北京诺诚健华医药科技有限公司 | 2023-07-21 | — | — | CN | disclosed |
| CN-112334458-B | 3-indazolinone compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2022-11-08 | — | — | CN | disclosed |