Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.58 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.42 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 9/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 8/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22730011 | 1.00 | IDO1 (0.58) | IDO1LNPEPUSP30TLR8TLR7 | |
| SCHEMBL29924183 | 1.00 | IDO1 (0.58) | IDO1LNPEPUSP30TLR8TLR7 | |
| SCHEMBL21213954 | 1.00 | IDO1 (0.58) | IDO1LNPEPUSP30TLR8TLR7 | |
| SCHEMBL29923884 | 1.00 | IDO1 (0.58) | IDO1LNPEPUSP30TLR8TLR7 | |
| Bicarbonate SCHEMBL9280862 | 0.85 | IDO1 (0.54) | IDO1LNPEPUSP30TLR8TLR7 | |
| SCHEMBL17729954 | 0.84 | IDO1 (0.54) | IDO1LNPEPUSP30TLR8TLR7 | |
| SCHEMBL30209423 | 0.84 | IDO1 (0.54) | IDO1LNPEPUSP30TLR8TLR7 | |
| SCHEMBL28335167 | 0.84 | IDO1 (0.45) | IDO1LNPEPUSP30TLR8TLR7 | |
| SCHEMBL28335166 | 0.84 | IDO1 (0.45) | IDO1LNPEPUSP30TLR8TLR7 | |
| SCHEMBL19900796 | 0.82 | HDAC4 (0.49) | IDO1LNPEPTLR8TLR7BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111247119-B | Amidine and guanidine derivatives, preparation method and application thereof in medicines | 四川科伦博泰生物医药股份有限公司 | 2023-02-03 | — | — | CN | disclosed |
| US-11389445-B2 | Pentafluorosulfanyl-substituted amide derivatives, preparation methods thereof and medical uses thereof | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2022-07-19 | — | — | US | disclosed |
| CN-111630043-B | Compound containing ring, preparation method and application thereof in medicine | 四川科伦博泰生物医药股份有限公司 | 2022-02-15 | — | — | CN | disclosed |
| US-20210221808-A1 | 3-OXAZOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2021-07-22 | — | — | US | disclosed |
| CN-106999450-B | Immunomodulator | 弗莱塞斯生物科学公司 | 2021-07-09 | — | — | CN | disclosed |
| EP-3805212-A1 | 3-OXAZOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF | Beijing InnoCare Pharma Tech Co., Ltd. (CN) | 2021-04-14 | — | — | EP | disclosed |
| EP-3215142-B1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2021-03-24 | — | — | EP | disclosed |
| US-20210046069-A1 | PENTAFLUOROSULFANYL-SUBSTITUTED AMIDE DERIVATIVES, PREPARATION METHODS THEREOF AND MEDICAL USES THEREOF | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2021-02-18 | — | — | US | disclosed |
| CN-112334458-A | 3-indazolinone compound, preparation method and application thereof in medicine and pharmacology | 北京诺诚健华医药科技有限公司 | 2021-02-05 | — | — | CN | disclosed |
| EP-3747865-A1 | PENTAFLUOROSULFANYL-SUBSTITUTED AMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATION THEREOF | Beijing InnoCare Pharma Tech Co., Ltd. (CN) | 2020-12-09 | — | — | EP | disclosed |
| CN-111247119-A | Amidine and guanidine derivatives, preparation method and application thereof in medicines | 四川科伦博泰生物医药股份有限公司 | 2020-06-05 | — | — | CN | disclosed |
| WO-2019179369-A1 | RING-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL APPLICATION THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |
| WO-2019141095-A1 | AMIDINE AND GUANIDINE DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-07-25 | — | — | WO | disclosed |
| US-10206893-B2 | Immunoregulatory agents | FLEXUS BIOSCIENCES, INC. (US) | 2019-02-19 | — | — | US | disclosed |
| US-20180325889-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES, INC. | 2018-11-15 | — | — | US | disclosed |
| EP-3215142-A2 | IMMUNOREGULATORY AGENTS | Flexus Biosciences, Inc. (US) | 2017-09-13 | — | — | EP | disclosed |
| US-20170143649-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES INC (US) | 2017-05-25 | — | — | US | disclosed |
| US-9598422-B2 | Immunoregulatory agents | FLEXUS BIOSCIENCES, INC. (US) | 2017-03-21 | — | — | US | disclosed |
| US-20160137653-A1 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES, INC. | 2016-05-19 | — | — | US | disclosed |
| WO-2016073774-A2 | IMMUNOREGULATORY AGENTS | FLEXUS BIOSCIENCES, INC. (US) | 2016-05-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160137653-A1 | IMMUNOREGULATORY AGENTS | IDO1, IDO2, INMT | IDO1 1/4885LNPEP 1023/4885USP30 1692/4885 |
| US-10206893-B2 | Immunoregulatory agents | IDO1, IDO2, INMT | IDO1 1/4885LNPEP 1023/4885USP30 1692/4885 |
| US-20170143649-A1 | IMMUNOREGULATORY AGENTS | IDO1, IDO2, INMT | IDO1 1/4885LNPEP 1023/4885USP30 1692/4885 |
| US-20210221808-A1 | 3-OXAZOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL APPLICATION THEREOF | IDO1, IDO2, INMT | IDO1 1/4885LNPEP 1452/4885USP30 3256/4885 |
| US-20180325889-A1 | IMMUNOREGULATORY AGENTS | IDO1, IDO2, INMT | IDO1 1/4885LNPEP 1023/4885USP30 1692/4885 |
| US-20210046069-A1 | PENTAFLUOROSULFANYL-SUBSTITUTED AMIDE DERIVATIVES, PREPARATION METHODS THEREOF AND MEDICAL USES THEREOF | IDO1, IDO2, KYNU | IDO1 1/4885LNPEP 319/4885USP30 1606/4885 |
| US-11389445-B2 | Pentafluorosulfanyl-substituted amide derivatives, preparation methods thereof and medical uses thereof | IDO1, IDO2, KYNU | IDO1 1/4885LNPEP 319/4885USP30 1606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.