SCHEMBL29924232

SCHEMBL29924232

O=C1CCc2ccc(-c3ccc(OC(F)(F)F)cc3)cc2N1CCN1CCOCC1

nearest known ligand 0.52

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 1/20 0.49
BRD4 O60885 1/20 0.48
PRKDC P78527 1/20 0.43
EPHX2 P34913 2/20 0.43
ABL1 P00519 2/20 0.42
BCR P11274 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28901303 1.00 HRH3 (0.49) HRH3BRD4PRKDCEPHX2ABL1
SCHEMBL28901316 0.86 DRD2 (0.48)
SCHEMBL29924284 0.86 DRD2 (0.48)
SCHEMBL28901295 0.85 BRD4 (0.50) HRH3BRD4
SCHEMBL29924500 0.85 BRD4 (0.50) HRH3BRD4
SCHEMBL28901313 0.84 BRD4 (0.43) BRD4
SCHEMBL28901318 0.83 DRD2 (0.52) BRD4
SCHEMBL29924191 0.83 DRD2 (0.52) BRD4
SCHEMBL29924292 0.83 DRD2 (0.52) BRD4
SCHEMBL28901320 0.83 DRD2 (0.52) BRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115073370-A Novel alkylammonium compound or salt, isomer, preparation method and application thereof 成都硕德药业有限公司 2022-09-20 CN claimed
CN-115073370-B Novel alkylaminos or salts, isomers, preparation method and application thereof 成都硕德药业有限公司 2024-12-17 CN disclosed
CN-115073370-A Novel alkylammonium compound or salt, isomer, preparation method and application thereof 成都硕德药业有限公司 2022-09-20 CN disclosed