Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.47 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.45 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29149941 | 1.00 | MAPT (0.53) | MAPTL3MBTL1KMT2AALDH1A1LMNA | |
| SCHEMBL29079750 | 0.80 | GRM2 (0.48) | MAPTL3MBTL1KMT2AALDH1A1LMNA | |
| SCHEMBL29480815 | 0.80 | GRM2 (0.48) | MAPTL3MBTL1KMT2AALDH1A1LMNA | |
| SCHEMBL30306714 | 0.77 | KMT2A (0.56) | MAPTL3MBTL1KMT2AALDH1A1LMNA | |
| SCHEMBL28984550 | 0.77 | PTGS1 (0.57) | MAPTL3MBTL1KMT2AALDH1A1LMNA | |
| SCHEMBL28984551 | 0.77 | KMT2A (0.56) | MAPTL3MBTL1KMT2AALDH1A1LMNA | |
| SCHEMBL30306722 | 0.77 | PTGS1 (0.57) | MAPTL3MBTL1KMT2AALDH1A1LMNA | |
| SCHEMBL1098997 | 0.77 | KMT2A (0.50) | MAPTL3MBTL1KMT2AALDH1A1LMNA | |
| SCHEMBL1999968 | 0.76 | MAPT (0.52) | MAPTL3MBTL1KMT2AALDH1A1LMNA | |
| SCHEMBL226465 | 0.76 | UBE2T (0.70) | MAPTL3MBTL1KMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |