Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE2A | O00408 | 2/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29149900 | 1.00 | HSD17B10 (0.41) | HSD17B10HTTPDE2APDE10ANPC1 | |
| SCHEMBL27110991 | 0.90 | ACSS2 (0.41) | HTTALDH1A1KDM4EPKML3MBTL1 | |
| SCHEMBL30269574 | 0.90 | ACSS2 (0.41) | HTTALDH1A1KDM4EPKML3MBTL1 | |
| SCHEMBL25005481 | 0.87 | PDE2A (0.41) | HSD17B10HTTPDE2APDE10ANPC1 | |
| SCHEMBL29924247 | 0.87 | PDE2A (0.41) | HSD17B10HTTPDE2APDE10ANPC1 | |
| SCHEMBL25340969 | 0.78 | ACSS2 (0.44) | HTTALDH1A1KDM4EPKMLMNA | |
| SCHEMBL29555279 | 0.78 | ACSS2 (0.44) | HTTALDH1A1KDM4EPKMLMNA | |
| SCHEMBL25340079 | 0.77 | ACSS2 (0.43) | HTTALDH1A1KDM4EPKM | |
| SCHEMBL29946034 | 0.77 | ACSS2 (0.43) | HTTALDH1A1KDM4EPKM | |
| SCHEMBL25322110 | 0.77 | ACSS2 (0.42) | HTTALDH1A1KDM4EPKML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117177970-A | Polycyclic derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |