⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16812883 | 0.79 | — | — | |
| SCHEMBL12749364 | 0.77 | CYP1A2 (0.32) | — | |
| SCHEMBL10679666 | 0.76 | TSHR (0.40) | — | |
| SCHEMBL6441479 | 0.75 | FAAH (0.33) | — | |
| SCHEMBL5836235 | 0.75 | TTR (0.40) | — | |
| SCHEMBL7706439 | 0.75 | — | — | |
| SCHEMBL19273 | 0.74 | — | — | |
| SCHEMBL6885967 | 0.74 | MAPT (0.69) | — | |
| SCHEMBL36139 | 0.74 | MAPT (0.69) | — | |
| SCHEMBL5167665 | 0.74 | TSHR (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112672992-B | Process for producing cyclopropane compound | 住友化学株式会社 | 2024-02-09 | — | — | CN | claimed |
| CN-117049589-A | Treatment method for extracting copper hydroxide from copper-containing etching waste liquid | 安徽绿洲危险废物综合利用有限公司 | 2023-11-14 | — | — | CN | claimed |
| US-20210347759-A1 | METHOD FOR MANUFACTURING CYCLOPROPANE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2021-11-11 | — | — | US | claimed |
| EP-3848348-A1 | METHOD FOR MANUFACTURING CYCLOPROPANE COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2021-07-14 | — | — | EP | claimed |
| CN-112672992-A | Process for producing cyclopropane compound | 住友化学株式会社 | 2021-04-16 | — | — | CN | claimed |
| CN-104262621-A | Poly(alpha-carbonyl diazo alkane) as well as preparation method and application thereof | UNIV WUHAN | 2015-01-07 | — | — | CN | claimed |
| US-8558017-B2 | Ruthenium (II) catalysts for use in stereoselective cyclopropanations | VANDA PHARMACEUTICALS, INC. (US) | 2013-10-15 | — | — | US | claimed |
| US-20130023662-A9 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | VANDA PHARMECEUTICALS INC. (US) | 2013-01-24 | — | — | US | claimed |
| US-20120149906-A1 | RUTHENIUM (II) CATALYSTS FOR USE IN STEREOSELECTIVE CYCLOPROPANATIONS | VANDA PHARMECEUTICALS INC. (US) | 2012-06-14 | — | — | US | claimed |
| US-8097738-B2 | Ruthenium (II) catalysts for use in stereoselective cyclopropanations | VANDA PHARMACEUTICALS INC. (US) | 2012-01-17 | — | — | US | claimed |
| US-5939415-A | A!-annellated pyrrole derivatives and their use in pharmacology | MERCKLE GMBH (DE) | 1999-08-17 | — | — | US | claimed |
| WO-1998025892-A1 | INTEGRIN ANTAGONISTS | ELI LILLY AND COMPANY (US) | 1998-06-18 | — | — | WO | claimed |
| US-5532381-A | Process for preparing pyrrolizine derivatives | DONG KOOK PHARMACEUTICAL CO., LTD. (KR) | 1996-07-02 | — | — | US | claimed |
| US-H1064-H | Using diazo compound | SHELL OIL COMPANY (US) | 1992-06-02 | — | — | US | claimed |
| EP-0128012-B1 | NOVEL CHIRAL COPPER COMPLEX AND ASYMMETRIC SYNTHESIS OF CYCLOPROPANECARBOXYLATE DERIVATIVES USING SAID COMPLEX AS CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1986-11-20 | — | — | EP | claimed |
| US-4603218-A | Asymmetric synthesis of cyclopropanecarboxylate derivatives using chiral copper complex as catalyst | SUMITOMO CHEMICAL CO., LTD. (JP) | 1986-07-29 | — | — | US | claimed |
| US-4565810-A | ANTICHOLESTEROL | LEHNER A.G. (CH) | 1986-01-21 | — | — | US | claimed |
| EP-0128012-A2 | Novel chiral copper complex and asymmetric synthesis of cyclopropanecarboxylate derivatives using said complex as catalyst | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-12 | — | — | EP | claimed |
| EP-0124068-A1 | New derivatives of biliary acids, process for the production thereof and pharmaceutical compositions containing the same | LEHNER A.G. (CH) | 1984-11-07 | — | — | EP | claimed |
| US-4029690-A | WITH 2,5-DIMETHYL-2,4-HEXADIENE AND AN ALKYL DIAZOACETATE WITH A COPPER COMPLEX CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1977-06-14 | — | — | US | claimed |