Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.57 |
| ▸ | THRB | P10828 | 3/20 | 0.52 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24741290 | 0.91 | LMNA (0.67) | LMNARXFP1THRBTP53MAPT | |
| SCHEMBL29924748 | 0.88 | LMNA (0.60) | LMNARXFP1THRBTP53MAPT | |
| SCHEMBL24619415 | 0.88 | LMNA (0.60) | LMNARXFP1THRBTP53MAPT | |
| SCHEMBL29924863 | 0.87 | LMNA (0.57) | LMNARXFP1THRBAPPTP53 | |
| SCHEMBL24741800 | 0.87 | LMNA (0.59) | LMNARXFP1THRBTP53MAPT | |
| SCHEMBL24741270 | 0.87 | LMNA (0.57) | LMNARXFP1THRBAPPTP53 | |
| SCHEMBL24619355 | 0.85 | LMNA (0.76) | LMNARXFP1THRBTP53MAPT | |
| SCHEMBL24619206 | 0.85 | LMNA (0.55) | LMNARXFP1THRBAPPTP53 | |
| SCHEMBL29925137 | 0.83 | LMNA (0.53) | LMNARXFP1THRBAPPTP53 | |
| SCHEMBL29056718 | 0.83 | LMNA (0.53) | LMNARXFP1THRBAPPTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4274569-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| CN-116635028-A | Modulators of c-MYC mRNA translation and their use in the treatment of cancer | 艾尼莫生物科技公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |