Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.44 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.44 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 3/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29925016 | 0.84 | HDAC1 (0.52) | BRD9BAZ2BBAZ2AGRM2NAMPT | |
| SCHEMBL24999627 | 0.80 | GRM2 (0.49) | GRM2NAMPTKDM4AHDAC1GLS | |
| SCHEMBL29769069 | 0.80 | GRM2 (0.49) | GRM2NAMPTKDM4AHDAC1GLS | |
| SCHEMBL12231247 | 0.79 | GRM2 (0.49) | GRM2NAMPTKDM4AHDAC1GLS | |
| SCHEMBL29924728 | 0.79 | GRM2 (0.49) | GRM2NAMPTKDM4AHDAC1GLS | |
| SCHEMBL24822620 | 0.78 | GRM2 (0.44) | GRM2NAMPTKDM4AHDAC1L3MBTL1 | |
| SCHEMBL26828546 | 0.78 | EPHX2 (0.42) | KCNA5GRM2NAMPTKDM4AHDAC1 | |
| SCHEMBL29369357 | 0.77 | HDAC1 (0.51) | GRM2NAMPTKDM4AHDAC1L3MBTL1 | |
| SCHEMBL25470355 | 0.77 | KCNA5 (0.52) | KCNA5BRD9BAZ2BBAZ2AGRM2 | |
| SCHEMBL31738223 | 0.76 | GRM2 (0.49) | GRM2NAMPTKDM4AHDAC1GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4274569-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |