Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 3/20 | 0.52 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25470479 | 0.88 | KCNA5 (0.50) | KCNA5KDM4AALOX5APFEN1HDAC1 | |
| SCHEMBL25471591 | 0.85 | AAK1 (0.45) | KCNA5KDM4AALOX5APFEN1HDAC1 | |
| SCHEMBL29467997 | 0.82 | KDM4A (0.41) | KCNA5KDM4AHDAC1CTSSCTSK | |
| SCHEMBL25471532 | 0.82 | KCNA5 (0.53) | KCNA5KDM4AHDAC1MALT1NQO2 | |
| SCHEMBL31296532 | 0.80 | SCN9A (0.50) | ALOX5APFEN1MALT1IDO1PDK2 | |
| SCHEMBL25470614 | 0.80 | SCN9A (0.50) | ALOX5APFEN1MALT1IDO1PDK2 | |
| SCHEMBL2002789 | 0.80 | KDM4A (0.41) | KCNA5KDM4AHDAC1CTSSCTSK | |
| SCHEMBL25470761 | 0.79 | MALT1 (0.45) | KCNA5KDM4AALOX5APFEN1MALT1 | |
| SCHEMBL8254926 | 0.79 | KCNA5 (0.61) | KCNA5KDM4AHDAC1MALT1IDO1 | |
| SCHEMBL4590703 | 0.78 | RIPK1 (0.60) | KCNA5KDM4ACTSSCTSKRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078127-A1 | MACROCYCLIC SULFONAMIDE COMPOUND, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 中国药科大学 | 2023-05-11 | — | — | WO | disclosed |