Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 2/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.34 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.34 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.34 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL29924695 | 1.00 | MAPK8 (0.41) | MAPK8FGFR1KDM4EALDH1A1SMN1; SMN2 | |
| Formic Acid SCHEMBL30537910 | 1.00 | MAPK8 (0.41) | MAPK8FGFR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3477374 | 0.94 | MAPK8 (0.44) | MAPK8FGFR1KDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL30722219 | 0.93 | MAPK8 (0.43) | MAPK8FGFR1KDM4EALDH1A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL31290659 | 0.93 | MAPK8 (0.43) | MAPK8FGFR1KDM4EALDH1A1SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL29925165 | 0.86 | MAPK8 (0.39) | MAPK8FGFR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3477375 | 0.83 | MAPK8 (0.41) | MAPK8FGFR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4658884 | 0.81 | KDM4E (0.44) | MAPK8FGFR1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL30085742 | 0.73 | ADORA3 (0.36) | MAPK8FGFR1DYRK1AKMT2AMAP2K3 | |
| Hydrochloric Acid SCHEMBL31290652 | 0.71 | ADORA3 (0.35) | MAPK8FGFR1DYRK1AKMT2AMAP2K3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4274569-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | Anima Biotech Inc. (US) | 2023-11-15 | — | — | EP | disclosed |
| CN-116635028-A | Modulators of c-MYC mRNA translation and their use in the treatment of cancer | 艾尼莫生物科技公司 | 2023-08-22 | — | — | CN | disclosed |
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |