Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 13/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 12/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | FABP2 | P12104 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30200169 | 0.80 | PDE2A (0.39) | GAASMN1; SMN2FFAR1FFAR4SLC22A12 | |
| SCHEMBL30199155 | 0.80 | PDE2A (0.39) | GAASMN1; SMN2FFAR1FFAR4SLC22A12 | |
| SCHEMBL29098047 | 0.80 | PDE2A (0.39) | GAASMN1; SMN2FFAR1FFAR4SLC22A12 | |
| SCHEMBL29098016 | 0.80 | PDE2A (0.39) | GAASMN1; SMN2FFAR1FFAR4SLC22A12 | |
| SCHEMBL29098018 | 0.80 | PDE2A (0.39) | GAASMN1; SMN2FFAR1FFAR4SLC22A12 | |
| SCHEMBL10121063 | 0.79 | GAA (0.37) | GAASMN1; SMN2FFAR1FFAR4 | |
| SCHEMBL19182930 | 0.78 | PTGS1 (0.54) | PTGS1PTGS2MEN1KMT2AHIF1A | |
| SCHEMBL19182931 | 0.78 | PTGS1 (0.54) | PTGS1PTGS2MEN1KMT2AHIF1A | |
| SCHEMBL31117279 | 0.78 | PTGS1 (0.54) | PTGS1PTGS2MEN1KMT2AHIF1A | |
| SCHEMBL15912960 | 0.76 | MAP2K1 (0.39) | GAAFFAR1FFAR4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |