Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | APLNR | P35414 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29098016 | 1.00 | PDE2A (0.39) | PDE2AGAASMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL30200169 | 1.00 | PDE2A (0.39) | PDE2AGAASMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL29098047 | 1.00 | PDE2A (0.39) | PDE2AGAASMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL29098018 | 1.00 | PDE2A (0.39) | PDE2AGAASMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL7216331 | 0.85 | GAA (0.41) | GAASMN1; SMN2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL10121063 | 0.85 | GAA (0.37) | PDE2AGAASMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL8576534 | 0.82 | KIF11 (0.37) | CYP11B1CYP11B2FFAR1FFAR4ALDH1A1 | |
| SCHEMBL25465575 | 0.82 | PDE2A (0.39) | PDE2AGAASMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL30937752 | 0.81 | PDE2A (0.51) | PDE2AGAASMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL27485765 | 0.81 | GAA (0.35) | PDE2AGAASMN1; SMN2CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594669-B | Parallel ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2024-11-05 | — | — | CN | disclosed |
| CN-115594669-A | Fused ring derivative and preparation method and medical application thereof | 深圳信立泰药业股份有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |