Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 7/20 | 0.53 |
| ▸ | ERAP2 | Q6P179 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28353995 | 0.85 | LNPEP (0.53) | LNPEPERAP2HDAC1KDM4EKMT2A | |
| SCHEMBL2014323 | 0.83 | LNPEP (0.56) | LNPEPERAP2HDAC1KDM4EKMT2A | |
| SCHEMBL26237173 | 0.82 | LNPEP (0.51) | LNPEPERAP2HDAC1KDM4EKMT2A | |
| SCHEMBL28754420 | 0.82 | LNPEP (0.49) | LNPEPERAP2HDAC1KDM4EKMT2A | |
| SCHEMBL1205232 | 0.80 | LNPEP (0.57) | LNPEPERAP2HDAC1KDM4EKMT2A | |
| SCHEMBL31143248 | 0.80 | KMT2A (0.52) | KDM4EKMT2AMAPTALDH1A1LMNA | |
| SCHEMBL24265280 | 0.79 | HDAC1 (0.53) | LNPEPERAP2HDAC1KDM4EMAPT | |
| SCHEMBL763198 | 0.78 | LNPEP (0.62) | LNPEPERAP2HDAC1KDM4EMAPT | |
| SCHEMBL23703823 | 0.76 | LNPEP (0.51) | LNPEPERAP2HDAC1KDM4EKMT2A | |
| SCHEMBL23286924 | 0.76 | LNPEP (0.48) | LNPEPERAP2HDAC1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022228490-A1 | POLYCYCLIC DERIVATIVE MODULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2022-11-03 | — | — | WO | disclosed |